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51.
In this paper, we analyze empirically the relation between the growth of new technology-based firms and the human capital of founders, with the aim of teasing out the “wealth” and “capability” effects of human capital. For this purpose, we take advantage of a new data set relating to a sample composed of 506 Italian young firms that operate in high-tech industries in both manufacturing and services. In accordance with competence-based theories, the econometric estimates show that the nature of the education and of the prior work experience of founders exerts a key influence on growth. In fact, founders’ years of university education in economic and managerial fields and to a lesser extent in scientific and technical fields positively affect growth while education in other fields does not. Similarly prior work experience in the same industry of the new firm is positively associated with growth while prior work experience in other industries is not. Furthermore, it is the technical work experience of founders as opposed to their commercial work experience that determines growth. The fact that within the founding team there are individuals with prior entrepreneurial experiences also results in superior growth. Lastly, we provide evidence that there are synergistic gains from the combination of the complementary capabilities of founders relating to (i) economic-managerial and scientific-technical education and (ii) technical and commercial industry-specific work experiences. We conclude that the human capital of founders of new technology-based firms is not just a proxy for personal wealth. 相似文献
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53.
Two uses of anaphora resolution in summarization 总被引:4,自引:0,他引:4
Josef Steinberger Massimo Poesio Mijail A. Kabadjov Karel Jeek 《Information processing & management》2007,43(6):1663
We propose a new method for using anaphoric information in Latent Semantic Analysis (lsa), and discuss its application to develop an lsa-based summarizer which achieves a significantly better performance than a system not using anaphoric information, and a better performance by the rouge measure than all but one of the single-document summarizers participating in DUC-2002. Anaphoric information is automatically extracted using a new release of our own anaphora resolution system, guitar, which incorporates proper noun resolution. Our summarizer also includes a new approach for automatically identifying the dimensionality reduction of a document on the basis of the desired summarization percentage. Anaphoric information is also used to check the coherence of the summary produced by our summarizer, by a reference checker module which identifies anaphoric resolution errors caused by sentence extraction. 相似文献
54.
Fabio Massimo Francioni António José Figueiredo Marco Terribili Antonio Tessitore 《Journal of sports sciences》2016,34(10):966-972
This study aimed to observe the intraseasonal stability of anthropometric, technical and functional test results in academy soccer players of different age categories. In total, 103 participants (age range: 7.7–13.4 years) by 5 age categories of the same academy were recruited for this study. Players were submitted to a field-test battery comprising 3 anthropometric measurements (body mass, stature and body mass index), 6 soccer technical tests (to assess the ability of ball control, ball control with the head, pass accuracy, shooting accuracy, dribbling and dribbling with pass) and 3 functional tests (countermovement jump with the hands on the hip, countermovement jump with free hands and 15-m linear sprint) that was administered in 4 test sessions during the same season. Though anthropometric results showed a clear increment in each age category across the season, the fluctuation of technical test results depended on age category and test session. Moreover, a significant increase in the results of functional tests was observed in most of the age categories, in particular, for the assessment of lower power limb. In conclusion, collecting repeated intraseason measurements permits the identification of players’ fluctuations of performance across the season and allows coaches to make frequent adjustments of their programmes. 相似文献
55.
Massimo Giusti Barbara Massa Margherita Balestra Paola Calamaro Stefano Gay Simone Schiaffino Giovanni Turtulici Simonetta Zupo Eleonora Monti Gianluca Ansaldo 《Journal of Zhejiang University. Science. B》2017,18(7):555-566
The cytology of 130 indeterminate nodules (Thy 3) was retrospectively reviewed according to the British Thyroid Association 2014 classification. Nodules were divided into Thy 3a (atypical features) and Thy 3f (follicular lesion) categories. Histology was available as a reference for 97 nodules. Pre-surgical evaluations comprised biochemical tests, color-Doppler ultrasonography (US), semi-quantitative elastography-US (USE), contrast-enhanced US (CEUS), and mutation analysis from cytological slides. Thyroid malignancy was the final diagnosis for 19% of surgically-treated nodules. No statistically significant difference in the risk of malignancy was found between Thy 3a (26%) and Thy 3f (14%) nodules. Histology of the Thy 3a and Thy 3f nodules showed a higher incidence of Hurtle cell adenomas in Thy 3f (29%) than in Thy 3a (3%) nodules (P=0.01). The only pre-surgical difference concerned the BRAF V600E mutation, which was positive in some Thy 3a but not in any Thy 3f nodules (P=0.04). Receiver-operating characteristic (ROC) analysis was used to obtain cut-off values from US (score), USE (ELX 2/1 strain index), and CEUS (time-topeak index and peak index) data. The cut-off values were similar for Thy 3a and Thy 3f nodules. Data showed that malignancy can be suspected if the US score is >2, ELX 1/2 strain index >1, time-to-peak index >1, and peak index <1. In a sub-group of 24 revised nodules (12 Thy 3a and 12 Thy 3f) with histology as a reference, the diagnostic power of cumulative pre-surgical analysis by means of US, USE, and CEUS showed high positive and negative predictive values (83% and 100%, respectively) for the presence of malignancy in Thy 3a and Thy 3f nodules. In conclusion, in our series of revised Thy 3 nodules, malignancy was low and displayed no significant differences between Thy 3a and Thy 3f categories. The use of cut-offs based on histology as a reference could reduce surgery. Our data support the conviction that, in mutation-negative Thy 3a and Thy 3f nodules, observation should be the first choice when not all instrumental results are suspect. 相似文献
56.
Giusti M Melle G Fenocchio M Mortara L Cecoli F Caorsi V Ferone D Minuto F Rasore E 《Journal of Zhejiang University. Science. B》2011,12(3):163-173
Differentiated thyroid carcinoma (DTC) generally has a favorable outcome. Thyroid disease, treatments, stress, and comorbidity
can compromise health-related quality of life (QoL) and indirectly weigh upon the outcome. From 2004 to 2008, we evaluated
QoL longitudinally in 128 DTC subjects. During scheduled examinations, subjects were asked to undergo a semi-structured psychiatric
interview and five rated inventories. The same examination was conducted in 219 subjects after surgery for benign thyroid
pathology. Low scores represent a better QoL. DTC and control subjects were similar in terms of age, male/female ratio, concomitant
psychopharmacological treatments, and frequency of psychiatric diseases. In DTC subjects, Billewicz scale (BS) scores showed
an increasing trend over time, especially among females. The ad hoc thyroid questionnaire (TQ) scores were similar in both
groups and did not change over time, but at the end of the study ad hoc TQ and BS were significantly related. Ad hoc TQ scores
were also related to age on entry to the study. In both male and female DTC subjects, Hamilton’s tests for anxiety (HAM-A),
but not for depression (HAM-D), showed an improving trend. At the end of the study, HAM-A and HAM-D scores were comparable
to those of the control group. HAM-A and HAM-D were both positively correlated with the stage of cancer and the time between
diagnosis and treatment. Only HAM-D correlated with age on entry to the study. Kellner symptom questionnaire (KSQ) item scores
were higher in DTC subjects than in controls. The change over time in the items including anxiety, somatization, depression,
and hostility was significant. Somatization and hostility were more significantly reduced in DTC females than in DTC males.
Hostility scores were significantly lower in DTC subjects than in controls at the end of the study. Somatization and depression
were significantly related to staging on diagnosis and age on entry to the study. Our study confirms a wide variation of illness
perception in DTC subjects, which is generally unrelated to the favorable clinical follow-up of the disease. Psychological
evaluation during long-term follow-up improved QoL scores, which reached the same levels noted in subjects with a history
of thyroid surgery for benign thyroid pathology. Our data indicate that special attention should be paid to QoL in older DTC
subjects and those with more severe staging on diagnosis. 相似文献
57.
In search of complementary assets: The determinants of alliance formation of high-tech start-ups 总被引:2,自引:0,他引:2
Why do new technology-based firms (NTBFs) cooperate? Starting from Teece's [Teece, D.J., 1986. Profiting from technological innovation: implications for integration, collaboration, licensing, and public policy. Research Policy 15, 285-305] conceptual framework and taking advantage of subsequent literature on alliance formation in the resource and competence-based tradition and in the social structure perspective, we derive an empirical model that aims at highlighting the inducements and obstacles that these firms face in alliance formation according to firm-specific characteristics and the nature of the alliance. In particular, a distinction is made between exploitative commercial alliances and explorative technological alliances. The econometric estimates, based on a large sample of Italian young high-tech firms that are observed from 1994 to 2003, provide strong evidence supporting two key intuitions of Teece's work. First, the “combination of specialized complementary assets” appears to be a key driver of the formation of exploitative commercial alliances by NTBFs. More specifically, patent holding affects positively the likelihood to establish commercial alliances, but this propensity is found to rapidly decrease with firm size, suggesting that as long as NTBFs become larger and possess specialized commercial assets their urge for commercial alliances diminishes. Second, following the parallelism set forth by Teece between search for alliance partners and access to external financing, the analysis indicates that potentially beneficial alliances may not take place because of the high transaction costs faced by smaller NTBFs. In this respect, our results clearly support the view that sponsor institutions as public research organizations, venture and corporate venture capitalists may sensibly reduce these costs and that their role crucially depends on both the identity of the sponsor and the type of alliance. 相似文献
58.
Massimo Pigliucci 《Science & Education》2013,22(1):49-67
It is an unfortunate fact of academic life that there is a sharp divide between science and philosophy, with scientists often being openly dismissive of philosophy, and philosophers being equally contemptuous of the naiveté of scientists when it comes to the philosophical underpinnings of their own discipline. In this paper I explore the possibility of reducing the distance between the two sides by introducing science students to some interesting philosophical aspects of research in evolutionary biology, using biological theories of the origin of religion as an example. I show that philosophy is both a discipline in its own right as well as one that has interesting implications for the understanding and practice of science. While the goal is certainly not to turn science students into philosophers, the idea is that both disciplines cannot but benefit from a mutual dialogue that starts as soon as possible, in the classroom. 相似文献
59.
Massimo Daves Andrea Piccin Vincenzo Roccaforte Giuseppe Lippi 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2021,31(3)
IntroductionThe measurement of serum free light chain (FLC) represents a fundamental aspect on the assessment of patients with monoclonal gammopathies (MG). Different analytical methods for FLC have become available with the possibility to obtain different value with a substantial impact on the assessment of patients with MG. This study aimed to evaluate FLC results obtained with two different assays and how the difference value obtained can impact in the patient’s assessment.Materials and methodsNinety-three patient serum samples that underwent analysis for FLC with two different methods, Serum Freelite (The Binding Site, Birmingham, UK) and N-Latex FLC (Siemens, Marburg, Germany), were included in this retrospective study. Statistical analysis was performed to evaluate correlation, difference, and the grade of concordance between the results obtained with the two methods.ResultsSignificant statistical differences between the results obtained from the two methods were found (P < 0.05). A good correlation was found (0.99 for κ FLC, 0.95 for λ FLC, and 0.94 for the κ/λ ratio, respectively). We found a weighted kappa value of 0.65 for κ/λ ratio, 0.65 for λ FLC and 0.90 for κ FLC. A positive bias found with the Bland-Altman plot mirrors overestimation of κ FLC and κ/λ ratio with Freelite compared to N-Latex, whilst a negative bias underscores underestimation of λ FLC by Freelite compared to N-Latex.ConclusionAlthough in general the concordance between Freelite and N-Latex appears satisfactory, several discrepancies could be evidenced and consequently the two assays are not interchangeable. 相似文献
60.
Introduction: A perspective on Web Information Retrieval 总被引:1,自引:0,他引:1